Tubular reabsorption of amino acids in vitamin C deficiency.

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Tubular reabsorption of amino acids in vitamin C deficiency.

(1957), Seaman and Schwartz (1958), Meacham (1967), English and Maltby (1967), Matson (1969), and James and Lassman (1972). None of these authors has described a single patient presenting so many unusual features. The most important of these features were the numerous skeletal abnormalities and an outstanding massive buttress of bone instead of the usual spur. This sessile mass of central bone ...

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Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice.

Levels of the necessary nutrient vitamin C (ascorbate) are tightly regulated by intestinal absorption, tissue accumulation, and renal reabsorption and excretion. Ascorbate levels are controlled in part by regulation of transport through at least 2 sodium-dependent transporters: Slc23a1 and Slc23a2 (also known as Svct1 and Svct2, respectively). Previous work indicates that Slc23a2 is essential f...

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The role of tubular reabsorption in the renal excretion of bile acids.

1. The renal excretion of bile acids was studied in an isolated rat kidney preparation perfused with a protein-free medium. 2. Tubular reabsorption exceeded 95% for both non-sulphated and sulphated bile acids at filtered loads of less than 30 nmol/min. 3. At low filtered loads the reabsorption of taurocholate and taurochenodeoxycholate was almost complete. Efficient reabsorption of taurochenode...

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Recent advances in renal tubular calcium reabsorption.

PURPOSE OF REVIEW Knowledge of renal Ca2+ reabsorption has evolved greatly in recent years. This review focuses on two recent discoveries concerning passive and active Ca2+ reabsorption. RECENT FINDINGS The thiazide diuretics are known for their hypocalciuric effect. Recently, it has been demonstrated that TRPV5-knockout mice, in which active Ca2+ reabsorption in the distal convoluted tubule ...

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Deficiency of Vitamin C in South Asia

Vitamin C (L-ascorbic acid) is a water soluble vitamin which is an antioxidant and has a wide variety of biological functions for growth and development of the human body. It is essential for maintaining good health. The objective of this review is to share with the scientific community, the status of vitamin C in the South Asian populations compared to other populations in the world. The focus...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1973

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.48.5.402